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patient derived xenograft models of human cancer 2017 edition by peter w gout pdf
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Patient-derived xenograft (PDX) models of human cancer are preclinical models where tumor tissue from a cancer patient is implanted into immunodeficient mice. These models are used to study cancer biology, drug response, and personalized medicine. The 2017 edition of "Patient Derived Xenograft Models of Human Cancer" by Peter W. Gout provides an updated and comprehensive overview of the current state of PDX models, including their applications, advantages, limitations, and recent advances in the field. The book covers topics such as the establishment and characterization of PDX models, the use of PDX models in drug discovery and development, and the potential for PDX models to improve patient outcomes through personalized cancer therapy. Overall, this edition serves as a valuable resource for researchers, clinicians, and students interested in understanding and utilizing PDX models for cancer research and treatment.